kageyd
02-11-2010, 08:24 AM
ginai, here's a direct quote from the American College of Rheumatology website. Sounds as though your elevated CCP could be an early sign of RA, pre-symptoms, so your doc may well be on the right track. Bold letters mine. Kageyd
"The Use of Anti-cyclic Citrullinated Peptide (anti-CCP) Antibodies in RA
Bottom line:
Anti-CCP antibodies are potentially important surrogate markers for diagnosis and prognosis in rheumatoid arthritis (RA), because they:
* are as sensitive as, and more specific than, IgM rheumatoid factors (RF) in early and fully established disease
* may predict the eventual development into RA when found in undifferentiated arthritis
* are a marker of erosive disease in RA
* may be detected in healthy individuals years before onset of clinical RA"
"The Use of Anti-cyclic Citrullinated Peptide (anti-CCP) Antibodies in RA
Bottom line:
Anti-CCP antibodies are potentially important surrogate markers for diagnosis and prognosis in rheumatoid arthritis (RA), because they:
* are as sensitive as, and more specific than, IgM rheumatoid factors (RF) in early and fully established disease
* may predict the eventual development into RA when found in undifferentiated arthritis
* are a marker of erosive disease in RA
* may be detected in healthy individuals years before onset of clinical RA"